Lidocaine is a synthetic aminoethylamide with local anesthetic and antiarrhythmic properties lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage gated sodium channels thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. Xylocaine chemistry pharmacology and clinical applications you will receive an email whenever this article is corrected updated or cited in the literature. Estimated maximal safe dosages of tumescent lidocaine tumescent anesthesia and modified liposuction fda freedom of information foi lidocaine xylocaine chemistry pharmacology and clinical applications dr nils lofgren bengt lundqvist chapter 1 the discovery of xylocaine chapter 2 chemistry and pharmacology chapter 3 the . Xylocaine with epinephrine in multiple dose vials each ml also contains 1 mg methylparaben as antiseptic preservative the ph of these colutions is adjusted to approximately 45 33 to 55 with sodium hydroxide and or hydrochloric acid filled under nitrogen xylocaine clinical pharmacology mechanism of action
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